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Target
Beta-lactamase
Ligand
BDBM52030
Substrate
n/a
Meas. Tech.
FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts.
IC50
17583±n/a nM
Citation
 PubChem, PC FRET-based counterscreen for selective VIM-2 inhibitors: dose response biochemical high throughput screening assay to identify epi-absorbance assay artifacts. PubChem Bioassay (2009)[AID] 
Target
Name:
Beta-lactamase
Synonyms:
Beta lactamase
Type:
Enzyme Catalytic Domain
Mol. Mass.:
31513.38
Organism:
Pseudomonas aeruginosa
Description:
gi_114881106
Residue:
286
Sequence:
MSIQHFRVALIPFFAAFCLPVFAHPETLVKVKDAEDKLGARVGYIELDLNSGKILESFRPEERFPMMSTFKVLLCGAVLSRVDAGQEQLGRRIHYSQNDLVEYSPVTEKHLTDGMTVRELCSAAITMSDNTAANLLLTTIGGPKELTAFLHNMGDHVTRLDRWEPELNEAIPNDERDTTMPAAMATTLRKLLTGELLTLASRQQLIDWMEADKVAGPLLRSALPAGWFIADKSGAGERGSRGIIAALGPDGKPSRIVVIYTTGSQATMDERNRQIAEIGASLIKHW
  
Inhibitor
Name:
BDBM52030
Synonyms:
(2E)-2-(2-fluorobenzylidene)-3-keto-N-(3-morpholinopropyl)-4H-1,4-benzothiazine-6-carboxamide | (2E)-2-[(2-fluorophenyl)methylidene]-N-(3-morpholin-4-ylpropyl)-3-oxidanylidene-4H-1,4-benzothiazine-6-carboxamide | (2E)-2-[(2-fluorophenyl)methylidene]-N-(3-morpholin-4-ylpropyl)-3-oxo-4H-1,4-benzothiazine-6-carboxamide | (2E)-2-[(2-fluorophenyl)methylidene]-N-[3-(4-morpholinyl)propyl]-3-oxo-4H-1,4-benzothiazine-6-carboxamide | MLS001030664 | SMR000635170 | cid_6010071
Type:
Small organic molecule
Emp. Form.:
C23H24FN3O3S
Mol. Mass.:
441.518
SMILES:
Fc1ccccc1\C=C1\Sc2ccc(cc2NC1=O)C(=O)NCCCN1CCOCC1
Structure:
Search PDB for entries with ligand similarity: