Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52227
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
150000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52227
Synonyms:
3-Ethyl-2-[2-(5-nitro-furan-2-yl)-vinyl]-3H-quinazolin-4-one | 3-ethyl-2-[(E)-2-(5-nitro-2-furanyl)ethenyl]-4-quinazolinone | 3-ethyl-2-[(E)-2-(5-nitro-2-furyl)vinyl]quinazolin-4-one | 3-ethyl-2-[(E)-2-(5-nitrofuran-2-yl)ethenyl]quinazolin-4-one | MLS000122557 | SMR000119979 | cid_5731123
Type:
Small organic molecule
Emp. Form.:
C16H13N3O4
Mol. Mass.:
311.2921
SMILES:
CCn1c(\C=C\c2ccc(o2)[N+]([O-])=O)nc2ccccc2c1=O
Structure:
Search PDB for entries with ligand similarity: