Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM52483
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
9019±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52483
Synonyms:
4-(3,5-dimethylpyridin-1-ium-1-yl)-5-[(phenylcarbamothioylhydrazinylidene)methyl]-1,3-thiazol-2-olate | 4-(3,5-dimethylpyridin-1-ium-1-yl)-5-[(phenylthiocarbamoylhydrazono)methyl]thiazol-2-olate | 5-[[[anilino(sulfanylidene)methyl]hydrazinylidene]methyl]-4-(3,5-dimethyl-1-pyridin-1-iumyl)-2-thiazololate | MLS000585399 | SMR000204162 | cid_1180006
Type:
Small organic molecule
Emp. Form.:
C18H17N5OS2
Mol. Mass.:
383.49
SMILES:
Cc1cc(C)c[n+](c1)-c1[n-]c(=O)sc1C=NNC(=S)Nc1ccccc1 |w:15.17|
Structure:
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