Reaction Details Report a problem with these data
Target
Zinc finger protein mex-5
Ligand
BDBM51075
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
38486±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM51075
Synonyms:
2-[[[(Z)-[2-keto-4-(3-methylpyridin-1-ium-1-yl)-3-thiazolin-5-ylidene]methyl]amino]carbamoyl]phenolate | 2-[[[(Z)-[4-(3-methyl-1-pyridin-1-iumyl)-2-oxo-5-thiazolylidene]methyl]hydrazo]-oxomethyl]phenolate | 2-[[[(Z)-[4-(3-methylpyridin-1-ium-1-yl)-2-oxidanylidene-1,3-thiazol-5-ylidene]methyl]amino]carbamoyl]phenolate | 2-[[[(Z)-[4-(3-methylpyridin-1-ium-1-yl)-2-oxo-1,3-thiazol-5-ylidene]methyl]amino]carbamoyl]phenolate | MLS000589575 | SMR000212994 | cid_15944865
Type:
Small organic molecule
Emp. Form.:
C17H14N4O3S
Mol. Mass.:
354.383
SMILES:
Cc1ccc[n+](c1)-c1[nH]c(=O)sc1C=NNC(=O)c1ccccc1[O-] |w:14.16|
Structure:
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