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Target
Zinc finger protein mex-5
Ligand
BDBM52844
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2
EC50
421±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of Mex-5 Binding to TCR-2 PubChem Bioassay (2009)[AID] 
Target
Name:
Zinc finger protein mex-5
Synonyms:
MEX5_CAEEL | RecName: Full=Zinc finger protein mex-5 | mex-5
Type:
Enzyme Catalytic Domain
Mol. Mass.:
52832.78
Organism:
Caenorhabditis elegans
Description:
gi_55976631
Residue:
468
Sequence:
MKAASNSVSSAGGSVSPTTTQPPLPPGQSSHPQIYDQQMQYYFAAAMPNQPMATYAAQNGSSQQYAPAAPYYQDANGQYVQVPANGSMAPQQHMMVSGQPYLYMAQPQQGAQQVMQSGQPQLIYYQQSMAPQAAPMYFHPMQAAPMLPEQMGVMPHTQPAIPPQQQPRQVGVEISSTRTAPLTSSTPLPTSLEYETVQRDNRNRNIQFRYHRVMEHDELPIDEISKITLDNHNDDTMSAEKENHFHEHRGEKFGRRGFPIPETDSQQPPNYKTRLCMMHASGIKPCDMGARCKFAHGLKELRATDAPARYPNNKYKTKLCKNFARGGTGFCPYGLRCEFVHPTDKEFQNIPPYQRMSHDDQDYDQDVIPEDYVVARHQPRFMRTGGRATTPTKVMLKHRNVAGSMMCLSNAGRDLQAGGDYNQPESNEDDLPPHLRRNRRENPPMNKRRTSLSTKWTSEENLGLRGHY
  
Inhibitor
Name:
BDBM52844
Synonyms:
4-[(5,6-dioxo-3-pyridinyl)hydrazo]benzenesulfonamide | 4-[2-(5,6-dioxopyridin-3-yl)hydrazinyl]benzenesulfonamide | 4-[2-[5,6-bis(oxidanylidene)pyridin-3-yl]hydrazinyl]benzenesulfonamide | 4-[N'-(5,6-diketo-3-pyridyl)hydrazino]benzenesulfonamide | MLS000738238 | SMR000528590 | cid_5382140
Type:
Small organic molecule
Emp. Form.:
C11H10N4O4S
Mol. Mass.:
294.287
SMILES:
NS(=O)(=O)c1ccc(cc1)N=Nc1c[nH]c(=O)c(O)c1 |w:10.10|
Structure:
Search PDB for entries with ligand similarity: