Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52878
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
300000±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52878
Synonyms:
2,2-dimethyl-5-veratrylidene-1,3-dioxane-4,6-quinone | 5-[(3,4-dimethoxyphenyl)methylidene]-2,2-dimethyl-1,3-dioxane-4,6-dione | Isopropylidene 3,4-dimethoxybenzylidene malonate | MLS000756816 | SMR000529081 | cid_370314
Type:
Small organic molecule
Emp. Form.:
C15H16O6
Mol. Mass.:
292.2839
SMILES:
[#6]-[#8]-c1ccc(\[#6]=[#6]-2/[#6](=O)-[#8]C([#6])([#6])[#8]-[#6]-2=O)cc1-[#8]-[#6]
Structure:
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