Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52967
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
17687±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52967
Synonyms:
4-O-(3-cyclopropyl-7-methyl-6,8-dioxoisochromen-7-yl) 1-O-methyl butanedioate | CMLD003356 | MLS000438826 | O4-[3-cyclopropyl-7-methyl-6,8-bis(oxidanylidene)isochromen-7-yl] O1-methyl butanedioate | SMR000452575 | butanedioic acid O4-(3-cyclopropyl-7-methyl-6,8-dioxo-2-benzopyran-7-yl) ester O1-methyl ester | cid_16759455 | succinic acid O4-(3-cyclopropyl-6,8-diketo-7-methyl-isochromen-7-yl) ester O1-methyl ester
Type:
Small organic molecule
Emp. Form.:
C18H18O7
Mol. Mass.:
346.3313
SMILES:
COC(=O)CCC(=O)OC1(C)C(=O)C=C2C=C(OC=C2C1=O)C1CC1 |c:15,18,t:13|
Structure:
Search PDB for entries with ligand similarity: