Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM40697
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
3632±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM40697
Synonyms:
4-(2,3-dihydroimidazo[2,1-b][1,3]thiazol-6-yl)-1,2-benzenediol | 4-(2,3-dihydroimidazo[2,1-b][1,3]thiazol-6-yl)benzene-1,2-diol | 4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)benzene-1,2-diol | 4-(2,3-dihydroimidazo[2,1-b]thiazol-6-yl)pyrocatechol | MLS000530540 | SMR000135520 | cid_877570
Type:
Small organic molecule
Emp. Form.:
C11H10N2O2S
Mol. Mass.:
234.274
SMILES:
Oc1ccc(cc1O)-c1cn2CCSc2n1
Structure:
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