Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52355
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
43536±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52355
Synonyms:
2,4-Dichloro-N-(5-oxo-4,5-dihydro-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)-benzamide | 2,4-bis(chloranyl)-N-(5-oxidanylidene-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)benzamide | 2,4-dichloro-N-(5-keto-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)benzamide | 2,4-dichloro-N-(5-oxo-1H-[1,2,4]triazolo[1,5-a]pyrimidin-7-yl)benzamide | MLS000552068 | SMR000145793 | cid_1846158
Type:
Small organic molecule
Emp. Form.:
C12H7Cl2N5O2
Mol. Mass.:
324.122
SMILES:
Clc1ccc(C(=O)Nc2cc(=O)[nH]c3ncnn23)c(Cl)c1
Structure:
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