Reaction Details Report a problem with these data
Target
POsterior Segregation
Ligand
BDBM52609
Substrate
n/a
Meas. Tech.
Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA
EC50
16267±n/a nM
Citation
 PubChem, PC Fluorescent Polarization Homogeneous Dose Response HTS to Indentify Inhibitors of POS-1 Binding to mex-3-RNA PubChem Bioassay (2009)[AID] 
Target
Name:
POsterior Segregation
Synonyms:
POsterior Segregation family member (pos-1)
Type:
Enzyme Catalytic Domain
Mol. Mass.:
29838.90
Organism:
Caenorhabditis elegans
Description:
gi_17562800
Residue:
264
Sequence:
MADNDFLSGEAIMVFKKEILDSHSDFTRSLSHQSASPEAYDQENVFSQDFQPFMKQDKETQNSASQPTSEQSLANRDPCTVPDDLREEMMRQRRKEDAFKTALCDAYKRSQACSYGDQCRFAHGVHELRLPMNPRGRNHPKYKTVLCDKFSMTGNCKYGTRCQFIHKIVDGNAAKLASGAHANTSSKSPARNAAAHNHSLFVPQGSTDRSMDLNQSLPIRQSDLVRAFARATRLDVSGYNSTAQLAQYFESQFQRIQQLSSHHH
  
Inhibitor
Name:
BDBM52609
Synonyms:
1-(4-hydroxyphenyl)-3-[(2-ketoindol-3-yl)amino]thiourea | 1-(4-hydroxyphenyl)-3-[(2-oxidanylideneindol-3-yl)amino]thiourea | 1-(4-hydroxyphenyl)-3-[(2-oxo-3-indolyl)amino]thiourea | 1-(4-hydroxyphenyl)-3-[(2-oxoindol-3-yl)amino]thiourea | 1H-indole-2,3-dione 3-[N-(4-hydroxyphenyl)thiosemicarbazone] | MLS000673957 | SMR000298023 | cid_5345764
Type:
Small organic molecule
Emp. Form.:
C15H12N4O2S
Mol. Mass.:
312.346
SMILES:
Oc1ccc(NC(=S)NNC2=c3ccccc3=NC2=O)cc1 |c:10,17|
Structure:
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