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Target
Tyrosine-protein phosphatase non-receptor type 7
Ligand
BDBM53578
Substrate
n/a
Meas. Tech.
HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target
IC50
100000±n/a nM
Citation
 PubChem, PC HTS Discovery of Chemical Inhibitors of HePTP, a Leukemia Target PubChem Bioassay (2008)[AID] 
Target
Name:
Tyrosine-protein phosphatase non-receptor type 7
Synonyms:
He-PTP | Hematopoietic protein-tyrosine phosphatase | Hematopoietic protein-tyrosine phosphatase (HEPTP) | PTN7_HUMAN | PTPN7 | Protein-tyrosine phosphatase LC-PTP | Tyrosine-protein phosphatase non-receptor type 7 | Tyrosine-protein phosphatase non-receptor type 7 (HEPTP)
Type:
Protein
Mol. Mass.:
40530.79
Organism:
Homo sapiens (Human)
Description:
P35236
Residue:
360
Sequence:
MVQAHGGRSRAQPLTLSLGAAMTQPPPEKTPAKKHVRLQERRGSNVALMLDVRSLGAVEPICSVNTPREVTLHFLRTAGHPLTRWALQRQPPSPKQLEEEFLKIPSNFVSPEDLDIPGHASKDRYKTILPNPQSRVCLGRAQSQEDGDYINANYIRGYDGKEKVYIATQGPMPNTVSDFWEMVWQEEVSLIVMLTQLREGKEKCVHYWPTEEETYGPFQIRIQDMKECPEYTVRQLTIQYQEERRSVKHILFSAWPDHQTPESAGPLLRLVAEVEESPETAAHPGPIVVHCSAGIGRTGCFIATRIGCQQLKARGEVDILGIVCQLRLDRGGMIQTAEQYQFLHHTLALYAGQLPEEPSP
  
Inhibitor
Name:
BDBM53578
Synonyms:
MLS000103771 | N-(4-methoxy-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)-2-thiophenecarboxamide | N-(4-methoxy-3-prop-2-ynyl-1,3-benzothiazol-2-ylidene)thiophene-2-carboxamide | N-(4-methoxy-3-propargyl-1,3-benzothiazol-2-ylidene)thiophene-2-carboxamide | SMR000017825 | cid_2151298
Type:
Small organic molecule
Emp. Form.:
C16H12N2O2S2
Mol. Mass.:
328.409
SMILES:
COc1cccc2s\c(=N/C(=O)c3cccs3)n(CC#C)c12
Structure:
Search PDB for entries with ligand similarity: