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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM61176
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
990±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM61176
Synonyms:
3-[[(E)-(3-nitro-6-oxidanylidene-cyclohexa-2,4-dien-1-ylidene)methyl]amino]-2-(phenoxymethyl)quinazolin-4-one | 3-[[(E)-(3-nitro-6-oxo-1-cyclohexa-2,4-dienylidene)methyl]amino]-2-(phenoxymethyl)-4-quinazolinone | 3-[[(E)-(3-nitro-6-oxocyclohexa-2,4-dien-1-ylidene)methyl]amino]-2-(phenoxymethyl)quinazolin-4-one | 3-[[(E)-(6-keto-3-nitro-cyclohexa-2,4-dien-1-ylidene)methyl]amino]-2-(phenoxymethyl)quinazolin-4-one | 3-{[1-(2-Hydroxy-5-nitro-phenyl)-meth-(E)-ylidene]-amino}-2-phenoxymethyl-3H-quinazolin-4-one | MLS000588760 | SMR000212435 | cid_5521968
Type:
Small organic molecule
Emp. Form.:
C22H16N4O5
Mol. Mass.:
416.3862
SMILES:
[O-][N+](=O)c1ccc(=O)[c-](\C=[NH+]\n2c(COc3ccccc3)nc3ccccc3c2=O)c1
Structure:
Search PDB for entries with ligand similarity: