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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM34893
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
1600±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM34893
Synonyms:
6-N-(benzylideneamino)-2-N,2-N,4-N,4-N-tetramethylpyrimidine-2,4,6-triamine | MLS000709098 | N2,N2,N4,N4-tetramethyl-N6-[(phenylmethylene)amino]pyrimidine-2,4,6-triamine | N2,N2,N4,N4-tetramethyl-N6-[(phenylmethylidene)amino]pyrimidine-2,4,6-triamine | SMR000282965 | [4-(N'-benzalhydrazino)-6-(dimethylamino)pyrimidin-2-yl]-dimethyl-amine | [4-[(N''Z)-N''-benzalhydrazino]-6-(dimethylamino)pyrimidin-2-yl]-dimethyl-amine | [4-[(N'Z)-N'-benzalhydrazino]-6-(dimethylamino)pyrimidin-2-yl]-dimethyl-amine | cid_2853497
Type:
Small organic molecule
Emp. Form.:
C15H20N6
Mol. Mass.:
284.3595
SMILES:
CN(C)c1cc(N=NCc2ccccc2)nc(n1)N(C)C |w:6.5|
Structure:
Search PDB for entries with ligand similarity: