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Target
SUMO-conjugating enzyme UBC9
Ligand
BDBM61222
Substrate
n/a
Meas. Tech.
AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation
IC50
35140±n/a nM
Citation
 PubChem, PC AlphaScreen confirmatory assay for validation of inhibitors of SUMOylation PubChem Bioassay (2010)[AID] 
Target
Name:
SUMO-conjugating enzyme UBC9
Synonyms:
UBC9 | UBC9_HUMAN | UBCE9 | UBE2I | ubiquitin-conjugating enzyme E2I
Type:
Enzyme Catalytic Domain
Mol. Mass.:
18011.66
Organism:
Homo sapiens (Human)
Description:
gi_4507785
Residue:
158
Sequence:
MSGIALSRLAQERKAWRKDHPFGFVAVPTKNPDGTMNLMNWECAIPGKKGTPWEGGLFKLRMLFKDDYPSSPPKCKFEPPLFHPNVYPSGTVCLSILEEDKDWRPAITIKQILLGIQELLNEPNIQDPAQAEAYTIYCQNRVEYEKRVRAQAKKFAPS
  
Inhibitor
Name:
BDBM61222
Synonyms:
Imidazo[2,1-a]isoquinoline-2-carboxylic acid [1-(5-nitro-furan-2-yl)-meth-(E)-ylidene]-hydrazide | MLS000333710 | N-[(5-nitro-2-furanyl)methylideneamino]-2-imidazo[2,1-a]isoquinolinecarboxamide | N-[(5-nitro-2-furyl)methyleneamino]imidaz[2,1-a]isoquinoline-2-carboxamide | N-[(5-nitrofuran-2-yl)methylideneamino]imidazo[2,1-a]isoquinoline-2-carboxamide | SMR000437838 | cid_933233
Type:
Small organic molecule
Emp. Form.:
C17H11N5O4
Mol. Mass.:
349.3003
SMILES:
[O-][N+](=O)c1ccc(\C=N\NC(=O)c2cn3ccc4ccccc4c3n2)o1
Structure:
Search PDB for entries with ligand similarity: