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Target
Ras-related protein Rab-2A
Ligand
BDBM54713
Substrate
n/a
Meas. Tech.
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
EC50
5224±n/a nM
Citation
 PubChem, PC Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related protein Rab-2A
Synonyms:
RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A.
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23545.28
Organism:
Canis lupus familiaris
Description:
gi_46577642
Residue:
212
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
  
Inhibitor
Name:
BDBM54713
Synonyms:
1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-[5-(4-methoxyphenyl)-1H-pyrrol-2-yl]-1-propanone | 1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-3-[5-(4-methoxyphenyl)-1H-pyrrol-2-yl]propan-1-one | 1-[4-(2,5-dimethylphenyl)piperazino]-3-[5-(4-methoxyphenyl)-1H-pyrrol-2-yl]propan-1-one | KUC103448N | UNM-0000306165 | cid_44193699
Type:
Small organic molecule
Emp. Form.:
C26H31N3O2
Mol. Mass.:
417.5432
SMILES:
COc1ccc(cc1)-c1ccc(CCC(=O)N2CCN(CC2)c2cc(C)ccc2C)[nH]1
Structure:
Search PDB for entries with ligand similarity: