Reaction Details Report a problem with these data
Target
Cell division control protein 42 homolog
Ligand
BDBM54546
Substrate
n/a
Meas. Tech.
Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype
Ki
1310±n/a nM
Citation
 PubChem, PC Oxadiazole SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Cdc42 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Cell division control protein 42 homolog
Synonyms:
CDC42 | CDC42_HUMAN | Cell division control protein 42 homolog | G25K GTP-binding protein | cell division cycle 42 (GTP binding protein, 25kDa)
Type:
PROTEIN
Mol. Mass.:
21258.36
Organism:
Homo sapiens (Human)
Description:
ChEMBL_652970
Residue:
191
Sequence:
MQTIKCVVVGDGAVGKTCLLISYTTNKFPSEYVPTVFDNYAVTVMIGGEPYTLGLFDTAGQEDYDRLRPLSYPQTDVFLVCFSVVSPSSFENVKEKWVPEITHHCPKTPFLLVGTQIDLRDDPSTIEKLAKNKQKPITPETAEKLARDLKAVKYVECSALTQKGLKNVFDEAILAALEPPEPKKSRRCVLL
  
Inhibitor
Name:
BDBM54546
Synonyms:
1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]-1-butanone | 1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]butan-1-one | 1-[4-(2,5-dimethylphenyl)piperazino]-4-[3-(4-methoxyphenyl)-1,2,4-oxadiazol-5-yl]butan-1-one | KUC103353N | UNM-0000306067 | cid_25241703
Type:
Small organic molecule
Emp. Form.:
C25H30N4O3
Mol. Mass.:
434.5307
SMILES:
COc1ccc(cc1)-c1noc(CCCC(=O)N2CCN(CC2)c2cc(C)ccc2C)n1
Structure:
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