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Target
GTPase KRas [1-37]
Ligand
BDBM54694
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant
Ki
560±n/a nM
Comments
Extracted from aid = 2043 and tid = 3
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Ras activated mutant PubChem Bioassay (2009)[AID] 
Target
Name:
GTPase KRas [1-37]
Synonyms:
ras protein
Type:
Enzyme Catalytic Domain
Mol. Mass.:
4034.04
Organism:
Homo sapiens (Human)
Description:
gi_190938
Residue:
37
Sequence:
MTEYKLVVVGAGGVGKSALTIQLIQNHFVDEYDPTIE
  
Inhibitor
Name:
BDBM54694
Synonyms:
1-(2-nitrophenyl)-3-phenyl-2-propyn-1-one | 1-(2-nitrophenyl)-3-phenyl-prop-2-yn-1-one | 1-(2-nitrophenyl)-3-phenylprop-2-yn-1-one | UNM-0000306038 | cid_25227393
Type:
Small organic molecule
Emp. Form.:
C15H9NO3
Mol. Mass.:
251.2369
SMILES:
[O-][N+](=O)c1ccccc1C(=O)C#Cc1ccccc1
Structure:
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