Reaction Details Report a problem with these data
Target
Ras-related protein Rab-2A
Ligand
BDBM54698
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
EC50
30000±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related protein Rab-2A
Synonyms:
RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A.
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23545.28
Organism:
Canis lupus familiaris
Description:
gi_46577642
Residue:
212
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
  
Inhibitor
Name:
BDBM54698
Synonyms:
3-phenyl-1-(3-pyridinyl)-2-propyn-1-one | 3-phenyl-1-(3-pyridyl)prop-2-yn-1-one | 3-phenyl-1-pyridin-3-yl-prop-2-yn-1-one | 3-phenyl-1-pyridin-3-ylprop-2-yn-1-one | UNM-0000306056 | cid_326117
Type:
Small organic molecule
Emp. Form.:
C14H9NO
Mol. Mass.:
207.2274
SMILES:
O=C(C#Cc1ccccc1)c1cccnc1
Structure:
Search PDB for entries with ligand similarity: