Reaction Details Report a problem with these data
Target
Ras-related protein Rab-2A
Ligand
BDBM54693
Substrate
n/a
Meas. Tech.
Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype
Ki
110±n/a nM
Citation
 PubChem, PC Additional SAR compounds tested via Multiplex dose response to identify specific small molecule inhibitors of Ras and Ras-related GTPases specifically Rab2 wildtype PubChem Bioassay (2009)[AID] 
Target
Name:
Ras-related protein Rab-2A
Synonyms:
RAB2 | RAB2A | RAB2A_CANLF | Ras-related protein Rab-2A.
Type:
Enzyme Catalytic Domain
Mol. Mass.:
23545.28
Organism:
Canis lupus familiaris
Description:
gi_46577642
Residue:
212
Sequence:
MAYAYLFKYIIIGDTGVGKSCLLLQFTDKRFQPVHDLTIGVEFGARMITIDGKQIKLQIWDTAGQESFRSITRSYYRGAAGALLVYDITRRDTFNHLTTWLEDARQHSNSNMVIMLIGNKSDLESRREVKKEEGEAFAREHGLIFMETSAKTASNVEEAFINTAKEIYEKIQEGVFDINNEANGIKIGPQHAATNATHAGNQGGQQAGGGCC
  
Inhibitor
Name:
BDBM54693
Synonyms:
UNM-0000305812 | cid_23675324 | sodium;(2R)-2-(6-methoxy-2-naphthalenyl)propanoate | sodium;(2R)-2-(6-methoxy-2-naphthyl)propionate | sodium;(2R)-2-(6-methoxynaphthalen-2-yl)propanoate
Type:
Small organic molecule
Emp. Form.:
C14H13O3
Mol. Mass.:
229.2518
SMILES:
COc1ccc2cc(ccc2c1)[C@@H](C)C([O-])=O
Structure:
Search PDB for entries with ligand similarity: