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TargetDihydrodipicolinate synthase-like, mitochondrial
LigandBDBM267945
Substrate/Competitorn/a
Meas. Tech.Fluorescence based hOGA assay
pH7±n/a
Temperature298.15±n/a K
Ki 6.00±n/a nM
Commentsextracted
Citation Kaul, RMcEachern, EJVocadlo, DJZhou, YLiu, KSelnick, HGWei, ZMu, CWang, YWang, X Selective glycosidase inhibitors and uses thereof US Patent US9718854 Publication Date 8/1/2017
More Info.:Get all data from this article,  Assay Method
 
Dihydrodipicolinate synthase-like, mitochondrial
Name:4-hydroxy-2-oxoglutarate aldolase, mitochondrial
Synonyms:2-keto-4-hydroxyglutarate aldolase | C10orf65 | DHDPS-like protein | DHDPSL | Dihydrodipicolinate synthase-like, mitochondrial | HOGA1 | Probable KHG-aldolase | Protein 569272
Type:PROTEIN
Mol. Mass.:35253.21
Organism:Homo sapiens
Description:ChEMBL_461876
Residue:327
Sequence:
MLGPQVWSSVRQGLSRSLSRNVGVWASGEGKKVDIAGIYPPVTTPFTATAEVDYGKLEEN
LHKLGTFPFRGFVVQGSNGEFPFLTSSERLEVVSRVRQAMPKNRLLLAGSGCESTQATVE
MTVSMAQVGADAAMVVTPCYYRGRMSSAALIHHYTKVADLSPIPVVLYSVPANTGLDLPV
DAVVTLSQHPNIVGMKDSGGDVTRIGLIVHKTRKQDFQVLAGSAGFLMASYALGAVGGVC
ALANVLGAQVCQLERLCCTGQWEDAQKLQHRLIEPNAAVTRRFGIPGLKKIMDWFGYYGG
PCRAPLQELSPAEEEALRMDFTSNGWL
Blast this sequence in BindingDB or PDB
  Blast E-value cutoff:
BDBM267945
NameBDBM267945
Synonyms:(3aR,5R,6S,7R,7aR)-5- ((cyclopropylamino)methyl)-2- (dimethylamino)-5,6,7,7a-tetrahydro- 3aH-pyrano[3,2-d]thiazole-6,7-diol | US9718854, 33
TypeSmall organic molecule
Emp. Form.C12H21N3O3S
Mol. Mass.287.378
SMILESCN(C)C1=N[C@H]2[C@H](O[C@H](CNC3CC3)[C@@H](O)[C@@H]2O)S1 |r,t:3|
Structure
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n/a