Reaction Details Report a problem with these data
Target
Bcl-2-related protein A1
Ligand
BDBM33154
Substrate
n/a
Meas. Tech.
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1
EC50
8060±n/a nM
Citation
 PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bfl-1 PubChem Bioassay (2009)[AID] 
Target
Name:
Bcl-2-related protein A1
Synonyms:
B2LA1_HUMAN | BCL2A1 | BCL2L5 | BFL1 | Bcl-2-like protein 5 | GRS | HBPA1 | Hemopoietic-specific early response protein | Protein BFL-1 | Protein GRS
Type:
Apoptosis regulator protein
Mol. Mass.:
20130.01
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
175
Sequence:
MTDCEFGYIYRLAQDYLQCVLQIPQPGSGPSKTSRVLQNVAFSVQKEVEKNLKSCLDNVNVVSVDTARTLFNQVMEKEFEDGIINWGRIVTIFAFEGILIKKLLRQQIAPDVDTYKEISYFVAEFIMNNTGEWIRQNGGWENGFVKKFEPKSGWMTFLEVTGKICEMLSLLKQYC
  
Inhibitor
Name:
BDBM33154
Synonyms:
4-[(2-benzoxybenzyl)amino]phenol | 4-[(2-phenylmethoxyphenyl)methylamino]phenol | 4-{[2-(benzyloxy)benzyl]amino}phenol | MLS000704391 | SMR000231540 | US10112895, Compound 10 | cid_833990
Type:
Small organic molecule
Emp. Form.:
C20H19NO2
Mol. Mass.:
305.3704
SMILES:
Oc1ccc(NCc2ccccc2OCc2ccccc2)cc1
Structure:
Search PDB for entries with ligand similarity: