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Target
Bcl-2-like protein 2
Ligand
BDBM32266
Substrate
n/a
Meas. Tech.
Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W
EC50
20760±n/a nM
Citation
 PubChem, PC Confirmation dose response of hits from multiplexed high-throughput screen for small molecule regulators of Bcl-2 family protein interactions, specifically Bim-Bcl-W PubChem Bioassay (2009)[AID] 
Target
Name:
Bcl-2-like protein 2
Synonyms:
Apoptosis regulator Bcl-W | B2CL2_HUMAN | BCL-W | BCL2L2 | BCLW | Bcl-2-like protein 2 | Bcl2-L-2 | KIAA0271
Type:
Protein
Mol. Mass.:
20742.61
Organism:
Homo sapiens (Human)
Description:
n/a
Residue:
193
Sequence:
MATPASAPDTRALVADFVGYKLRQKGYVCGAGPGEGPAADPLHQAMRAAGDEFETRFRRTFSDLAAQLHVTPGSAQQRFTQVSDELFQGGPNWGRLVAFFVFGAALCAESVNKEMEPLVGQVQEWMVAYLETQLADWIHSSGGWAEFTALYGDGALEEARRLREGNWASVRTVLTGAVALGALVTVGAFFASK
  
Inhibitor
Name:
BDBM32266
Synonyms:
2,3-bis(2-furyl)-N-homoveratryl-quinoxaline-6-carboxamide | MLS000094619 | N-[2-(3,4-dimethoxyphenyl)ethyl]-2,3-bis(2-furanyl)-6-quinoxalinecarboxamide | N-[2-(3,4-dimethoxyphenyl)ethyl]-2,3-bis(furan-2-yl)quinoxaline-6-carboxamide | N-[2-(3,4-dimethoxyphenyl)ethyl]-2,3-di-2-furylquinoxaline-6-carboxamide | SMR000030172 | cid_3238500
Type:
Small organic molecule
Emp. Form.:
C27H23N3O5
Mol. Mass.:
469.4886
SMILES:
COc1ccc(CCNC(=O)c2ccc3nc(-c4ccco4)c(nc3c2)-c2ccco2)cc1OC
Structure:
Search PDB for entries with ligand similarity: