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Target
Kappa-type opioid receptor
Ligand
BDBM48648
Substrate
n/a
Meas. Tech.
HTS Image-Based Screen for Selective Agonists of the KOR Receptor
EC50
4271.88±n/a nM
Citation
 PubChem, PC HTS Image-Based Screen for Selective Agonists of the KOR Receptor PubChem Bioassay (2009)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM48648
Synonyms:
1-[4-(2,5-dimethylphenyl)-1-piperazinyl]-3-phenyl-2-(1-pyrrolyl)-1-propanone | 1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-3-phenyl-2-pyrrol-1-yl-propan-1-one | 1-[4-(2,5-dimethylphenyl)piperazin-1-yl]-3-phenyl-2-pyrrol-1-ylpropan-1-one | 1-[4-(2,5-dimethylphenyl)piperazino]-3-phenyl-2-pyrrol-1-yl-propan-1-one | MLS000522656 | SMR000127923 | cid_9550139
Type:
Small organic molecule
Emp. Form.:
C25H29N3O
Mol. Mass.:
387.5173
SMILES:
Cc1ccc(C)c(c1)N1CCN(CC1)C(=O)C(Cc1ccccc1)n1cccc1
Structure:
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