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Target
Kappa-type opioid receptor
Ligand
BDBM54786
Substrate
n/a
Meas. Tech.
HTS Image-Based Screen for Selective Agonists of the KOR Receptor
EC50
4154.12±n/a nM
Citation
 PubChem, PC HTS Image-Based Screen for Selective Agonists of the KOR Receptor PubChem Bioassay (2009)[AID] 
Target
Name:
Kappa-type opioid receptor
Synonyms:
K-OR-1 | KOR-1 | Kappa-opioid receptor (KOR) | Kappa-type opioid receptor (KOPR) | Kappa-type opioid receptor (KOR) | Kappa-type opioid receptor (Kappa) | OPIATE Kappa | OPRK | OPRK1 | OPRK_HUMAN | kappa opioid receptor (KOR)
Type:
G Protein-Coupled Receptor (GPCR)
Mol. Mass.:
42648.76
Organism:
Homo sapiens (Human)
Description:
P41145
Residue:
380
Sequence:
MDSPIQIFRGEPGPTCAPSACLPPNSSAWFPGWAEPDSNGSAGSEDAQLEPAHISPAIPVIITAVYSVVFVVGLVGNSLVMFVIIRYTKMKTATNIYIFNLALADALVTTTMPFQSTVYLMNSWPFGDVLCKIVISIDYYNMFTSIFTLTMMSVDRYIAVCHPVKALDFRTPLKAKIINICIWLLSSSVGISAIVLGGTKVREDVDVIECSLQFPDDDYSWWDLFMKICVFIFAFVIPVLIIIVCYTLMILRLKSVRLLSGSREKDRNLRRITRLVLVVVAVFVVCWTPIHIFILVEALGSTSHSTAALSSYYFCIALGYTNSSLNPILYAFLDENFKRCFRDFCFPLKMRMERQSTSRVRNTVQDPAYLRDIDGMNKPV
  
Inhibitor
Name:
BDBM54786
Synonyms:
(4-benzyl-1-{[1-(3-methylphenyl)-1H-imidazol-2-yl]methyl}piperidin-4-yl)methanol | MLS000735813 | SMR000317377 | [1-[[1-(3-methylphenyl)-2-imidazolyl]methyl]-4-(phenylmethyl)-4-piperidinyl]methanol | [1-[[1-(3-methylphenyl)imidazol-2-yl]methyl]-4-(phenylmethyl)piperidin-4-yl]methanol | [4-benzyl-1-[[1-(3-methylphenyl)imidazol-2-yl]methyl]piperidin-4-yl]methanol | [4-benzyl-1-[[1-(m-tolyl)imidazol-2-yl]methyl]-4-piperidyl]methanol | cid_16192384
Type:
Small organic molecule
Emp. Form.:
C24H29N3O
Mol. Mass.:
375.5066
SMILES:
Cc1cccc(c1)-n1ccnc1CN1CCC(CO)(Cc2ccccc2)CC1
Structure:
Search PDB for entries with ligand similarity: