Reaction Details Report a problem with these data
Target
Streptokinase A
Ligand
BDBM54879
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
EC50
83591±1187 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54879
Synonyms:
1-(10-phenothiazinyl)-2-(pyridin-4-ylthio)ethanone | 1-phenothiazin-10-yl-2-(4-pyridylthio)ethanone | 1-phenothiazin-10-yl-2-pyridin-4-ylsulfanyl-ethanone | 1-phenothiazin-10-yl-2-pyridin-4-ylsulfanylethanone | BRD-K50117178-001-01-0 | cid_44247469
Type:
Small organic molecule
Emp. Form.:
C19H14N2OS2
Mol. Mass.:
350.457
SMILES:
O=C(CSc1ccncc1)N1c2ccccc2Sc2ccccc12
Structure:
Search PDB for entries with ligand similarity: