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Target
Streptokinase A
Ligand
BDBM54898
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression
EC50
3942±1232 nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response Followup to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54898
Synonyms:
2-(1-pyrrolidinyl)-3-[3-(trifluoromethyl)phenyl]quinoline | 2-pyrrolidin-1-yl-3-[3-(trifluoromethyl)phenyl]quinoline | 2-pyrrolidino-3-[3-(trifluoromethyl)phenyl]quinoline | BRD-K96121336-001-04-1 | cid_3784173
Type:
Small organic molecule
Emp. Form.:
C20H17F3N2
Mol. Mass.:
342.3576
SMILES:
FC(F)(F)c1cccc(c1)-c1cc2ccccc2nc1N1CCCC1
Structure:
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