Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM39997
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM39997
Synonyms:
5-methyl-3-isoxazolecarboxylic acid [2-(5-bromo-2-thiophenyl)-2-oxoethyl] ester | 5-methylisoxazole-3-carboxylic acid [2-(5-bromo-2-thienyl)-2-keto-ethyl] ester | MLS000057232 | SMR000064814 | [2-(5-bromanylthiophen-2-yl)-2-oxidanylidene-ethyl] 5-methyl-1,2-oxazole-3-carboxylate | [2-(5-bromothiophen-2-yl)-2-oxoethyl] 5-methyl-1,2-oxazole-3-carboxylate | cid_2572725
Type:
Small organic molecule
Emp. Form.:
C11H8BrNO4S
Mol. Mass.:
330.155
SMILES:
Cc1cc(no1)C(=O)OCC(=O)c1ccc(Br)s1
Structure:
Search PDB for entries with ligand similarity: