Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM40714
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM40714
Synonyms:
2-(2-furanyl)-4-quinolinecarboxylic acid [2-[(2-methoxyphenyl)methylamino]-2-oxoethyl] ester | 2-(2-furyl)cinchoninic acid [2-keto-2-(o-anisylamino)ethyl] ester | MLS000565742 | SMR000152918 | [2-[(2-methoxyphenyl)methylamino]-2-oxidanylidene-ethyl] 2-(furan-2-yl)quinoline-4-carboxylate | [2-[(2-methoxyphenyl)methylamino]-2-oxoethyl] 2-(furan-2-yl)quinoline-4-carboxylate | cid_2092254
Type:
Small organic molecule
Emp. Form.:
C24H20N2O5
Mol. Mass.:
416.426
SMILES:
COc1ccccc1CNC(=O)COC(=O)c1cc(nc2ccccc12)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: