Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM54978
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM54978
Synonyms:
MLS000393762 | N-(4-chlorophenyl)-4-[(7-methyl-2-oxo-3-indolyl)hydrazo]-3-nitrobenzenesulfonamide | N-(4-chlorophenyl)-4-[2-(7-methyl-2-oxidanylidene-indol-3-yl)hydrazinyl]-3-nitro-benzenesulfonamide | N-(4-chlorophenyl)-4-[2-(7-methyl-2-oxoindol-3-yl)hydrazinyl]-3-nitrobenzenesulfonamide | N-(4-chlorophenyl)-4-[N'-(2-keto-7-methyl-indol-3-yl)hydrazino]-3-nitro-benzenesulfonamide | SMR000247883 | cid_5834626
Type:
Small organic molecule
Emp. Form.:
C21H16ClN5O5S
Mol. Mass.:
485.9
SMILES:
Cc1cccc2C(=[NH+]Nc3ccc(cc3[N+]([O-])=O)S(=O)(=O)Nc3ccc(Cl)cc3)C(=O)[N-]c12 |w:7.7|
Structure:
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