Reaction Details Report a problem with these data
Target
Core protein
Ligand
BDBM54985
Substrate
n/a
Meas. Tech.
TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization.
IC50
>49751±n/a nM
Citation
 PubChem, PC TR-FRET-based biochemical high-throughput dose response assay to identify inhibitors of Hepatitis C Virus (HCV) core protein dimerization. PubChem Bioassay (2009)[AID] 
Target
Name:
Core protein
Synonyms:
n/a
Type:
Enzyme Catalytic Domain
Mol. Mass.:
14237.71
Organism:
Hepatitis C virus
Description:
gi_83779224
Residue:
126
Sequence:
MSTNPKPQRKTKRNTNRRPQDVKFPGGGQIVGGVYLLPRRGPRLGVRATRKTSERSQPRGRRQPIPKDQRTTGKSWGKPGYPWPLYGNEGLGWAGWLLSPRGSRPSWGPNDPRHRSRNVGKVIDTL
  
Inhibitor
Name:
BDBM54985
Synonyms:
2-[(E)-3-(2-methoxyphenyl)prop-2-enylidene]-6-(phenylmethyl)-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7-dione | 2-[(E)-3-(2-methoxyphenyl)prop-2-enylidene]-6-(phenylmethyl)thiazolo[3,2-b][1,2,4]triazine-3,7-dione | 6-Benzyl-2-[(E)-3-(2-methoxy-phenyl)-prop-2-en-(Z)-ylidene]-thiazolo[3,2-b][1,2,4]triazine-3,7-dione | 6-benzyl-2-[(E)-3-(2-methoxyphenyl)prop-2-enylidene]-[1,3]thiazolo[3,2-b][1,2,4]triazine-3,7-dione | 6-benzyl-2-[(E)-3-(2-methoxyphenyl)prop-2-enylidene]thiazolo[3,2-b][1,2,4]triazine-3,7-quinone | MLS000769657 | SMR000434373 | cid_16745833
Type:
Small organic molecule
Emp. Form.:
C22H17N3O3S
Mol. Mass.:
403.454
SMILES:
COc1ccccc1\C=C\C=c1sc2nc(=O)c(Cc3ccccc3)nn2c1=O
Structure:
Search PDB for entries with ligand similarity: