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Target
Guanyl-specific ribonuclease T1
Ligand
BDBM55009
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1.
IC50
>55688±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. PubChem Bioassay (2009)[AID] 
Target
Name:
Guanyl-specific ribonuclease T1
Synonyms:
RNT1_ASPOR | rntA | unnamed protein product
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13952.57
Organism:
Aspergillus oryzae
Description:
gi_83774548
Residue:
130
Sequence:
MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVGSNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTGASGNNFVECT
  
Inhibitor
Name:
BDBM55009
Synonyms:
(6-methyl-4-phenyl-quinazolin-2-yl)-[(5-nitro-2-furyl)methyleneamino]amine | 5-nitro-2-furaldehyde (6-methyl-4-phenyl-2-quinazolinyl)hydrazone | 6-methyl-N-[(5-nitro-2-furanyl)methylideneamino]-4-phenyl-2-quinazolinamine | 6-methyl-N-[(5-nitrofuran-2-yl)methylideneamino]-4-phenyl-quinazolin-2-amine | 6-methyl-N-[(5-nitrofuran-2-yl)methylideneamino]-4-phenylquinazolin-2-amine | MLS000533723 | SMR000141161 | cid_2882204
Type:
Small organic molecule
Emp. Form.:
C20H15N5O3
Mol. Mass.:
373.3648
SMILES:
Cc1ccc2nc(N=NCc3ccc(o3)[N+]([O-])=O)nc(-c3ccccc3)c2c1 |w:7.6|
Structure:
Search PDB for entries with ligand similarity: