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Target
Guanyl-specific ribonuclease T1
Ligand
BDBM55011
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1.
IC50
>55688±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. PubChem Bioassay (2009)[AID] 
Target
Name:
Guanyl-specific ribonuclease T1
Synonyms:
RNT1_ASPOR | rntA | unnamed protein product
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13952.57
Organism:
Aspergillus oryzae
Description:
gi_83774548
Residue:
130
Sequence:
MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVGSNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTGASGNNFVECT
  
Inhibitor
Name:
BDBM55011
Synonyms:
(5E)-1-(4-methylphenyl)-5-[(5-nitro-2-furanyl)methylidene]-1,3-diazinane-2,4,6-trione | (5E)-1-(4-methylphenyl)-5-[(5-nitro-2-furyl)methylene]pyrimidine-2,4,6(1H,3H,5H)-trione | (5E)-1-(4-methylphenyl)-5-[(5-nitrofuran-2-yl)methylidene]-1,3-diazinane-2,4,6-trione | (5E)-5-[(5-nitro-2-furyl)methylene]-1-(p-tolyl)barbituric acid | MLS000723838 | SMR000305433 | cid_2201932
Type:
Small organic molecule
Emp. Form.:
C16H11N3O6
Mol. Mass.:
341.275
SMILES:
Cc1ccc(cc1)-n1c(=O)[nH]c([O-])c([CH+]c2ccc(o2)[N+]([O-])=O)c1=O
Structure:
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