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Target
Guanyl-specific ribonuclease T1
Ligand
BDBM51782
Substrate
n/a
Meas. Tech.
Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1.
IC50
>55688±n/a nM
Citation
 PubChem, PC Counterscreen for inhibitors of tRNA 2'-phosphotransferase (TPT1): fluorescence polarization-based biochemical high throughput dose response assay to identify inhibitors of RNAse T1. PubChem Bioassay (2009)[AID] 
Target
Name:
Guanyl-specific ribonuclease T1
Synonyms:
RNT1_ASPOR | rntA | unnamed protein product
Type:
Enzyme Catalytic Domain
Mol. Mass.:
13952.57
Organism:
Aspergillus oryzae
Description:
gi_83774548
Residue:
130
Sequence:
MMYSKLLTLTTLLLPTALALPSLVERACDYTCGSNCYSSSDVSTAQAAGYQLHEDGETVGSNSYPHKYNNYEGFDFSVSSPYYEWPILSSGDVYSGGSPGADRVVFNENNQLAGVITHTGASGNNFVECT
  
Inhibitor
Name:
BDBM51782
Synonyms:
(5E)-5-(2-furanylmethylidene)-1-(2-methylphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione | (5E)-5-(2-furfurylidene)-1-(o-tolyl)-2-thioxo-hexahydropyrimidine-4,6-quinone | (5E)-5-(furan-2-ylmethylidene)-1-(2-methylphenyl)-2-sulfanylidene-1,3-diazinane-4,6-dione | MLS001163797 | SMR000539168 | cid_1557339
Type:
Small organic molecule
Emp. Form.:
C16H12N2O3S
Mol. Mass.:
312.343
SMILES:
Cc1ccccc1N1C(=S)NC(=O)C(=Cc2ccco2)C1=O |w:14.15|
Structure:
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