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Target
Procathepsin L
Ligand
BDBM55122
Substrate
n/a
Meas. Tech.
QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1).
IC50
>59642±n/a nM
Citation
 PubChem, PC QFRET-based counterscreen for inhibitors of PFM18AAP: biochemical high throughput dose response assay for inhibitors of the Cathepsin L proteinase (CTSL1). PubChem Bioassay (2009)[AID] 
Target
Name:
Procathepsin L
Synonyms:
CATL1_HUMAN | CTSL | CTSL CTSL1 | CTSL1 | Cathepsin L | Cathepsin L1 | Cathepsin L1 heavy chain | Cathepsin L1 light chain | MEP | Major excreted protein | cathepsin L preproprotein
Type:
Enzyme
Mol. Mass.:
37557.19
Organism:
Homo sapiens (Human)
Description:
Purchased from Calbiochem (San Diego, CA).
Residue:
333
Sequence:
MNPTLILAAFCLGIASATLTFDHSLEAQWTKWKAMHNRLYGMNEEGWRRAVWEKNMKMIELHNQEYREGKHSFTMAMNAFGDMTSEEFRQVMNGFQNRKPRKGKVFQEPLFYEAPRSVDWREKGYVTPVKNQGQCGSCWAFSATGALEGQMFRKTGRLISLSEQNLVDCSGPQGNEGCNGGLMDYAFQYVQDNGGLDSEESYPYEATEESCKYNPKYSVANDTGFVDIPKQEKALMKAVATVGPISVAIDAGHESFLFYKEGIYFEPDCSSEDMDHGVLVVGYGFESTESDNNKYWLVKNSWGEEWGMGGYVKMAKDRRNHCGIASAASYPTV
  
Inhibitor
Name:
BDBM55122
Synonyms:
2-[(2-chlorophenyl)sulfonyl-(1,2,4-triazol-4-yl)amino]acetic acid methyl ester | MLS000026882 | SMR000122831 | [(2-Chloro-benzenesulfonyl)-[1,2,4]triazol-4-yl-amino]-acetic acid methyl ester | cid_778514 | methyl 2-[(2-chlorophenyl)sulfonyl-(1,2,4-triazol-4-yl)amino]acetate | methyl 2-[(2-chlorophenyl)sulfonyl-(1,2,4-triazol-4-yl)amino]ethanoate
Type:
Small organic molecule
Emp. Form.:
C11H11ClN4O4S
Mol. Mass.:
330.747
SMILES:
COC(=O)CN(n1cnnc1)S(=O)(=O)c1ccccc1Cl
Structure:
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