Reaction Details Report a problem with these data
Target
Neutrophil cytosol factor 1 [S99G]
Ligand
BDBM55695
Substrate
n/a
Meas. Tech.
Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs)
IC50
4580±n/a nM
Citation
 PubChem, PC Dose Response Confirmation for small molecular inhibitors for p47phox, a regulatory protein of NADPH oxidases (Noxs) PubChem Bioassay (2008)[AID] 
Target
Name:
Neutrophil cytosol factor 1 [S99G]
Synonyms:
NCF1 | NCF1_HUMAN | NOXO2 | SH3PXD1A | neutrophil cytosolic factor 1
Type:
Enzyme Catalytic Domain
Mol. Mass.:
44664.39
Organism:
Homo sapiens (Human)
Description:
gi_115298672
Residue:
390
Sequence:
MGDTFIRHIALLGFEKRFVPSQHYVYMFLVKWQDLSEKVVYRRFTEIYEFHKTLKEMFPIEAGAINPENRIIPHLPAPKWFDGQRAAENRQGTLTEYCGTLMSLPTKISRCPHLLDFFKVRPDDLKLPTDNQTKKPETYLMPKDGKSTATDITGPIILQTYRAIANYEKTSGSEMALSTGDVVEVVEKSESGWWFCQMKAKRGWIPASFLEPLDSPDETEDPEPNYAGEPYVAIKAYTAVEGDEVSLLEGEAVEVIHKLLDGWWVIRKDDVTGYFPSMYLQKSGQDVSQAQRQIKRGAPPRRSSIRNAHSIHQRSRKRLSQDAYRRNSVRFLQQRRRQARPGPQSPGSPLEEERQTQRSKPQPAVPPRPSADLILNRCSESTKRKLASAV
  
Inhibitor
Name:
BDBM55695
Synonyms:
(1Z)-1-[(4-nitroanilino)methylene]naphthalen-2-one | (1Z)-1-[(4-nitroanilino)methylidene]-2-naphthalenone | (1Z)-1-[(4-nitroanilino)methylidene]naphthalen-2-one | (1Z)-1-[[(4-nitrophenyl)amino]methylidene]naphthalen-2-one | 1-{[(E)-4-Nitro-phenylimino]-methyl}-naphthalen-2-ol | MLS000590229 | SMR000217280 | cid_5378393
Type:
Small organic molecule
Emp. Form.:
C17H12N2O3
Mol. Mass.:
292.2888
SMILES:
[O-][N+](=O)c1ccc(cc1)\[NH+]=C\[c-]1c2ccccc2ccc1=O
Structure:
Search PDB for entries with ligand similarity: