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Target
Kallikrein-5
Ligand
BDBM45362
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
1686.91±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM45362
Synonyms:
2,3-dimethoxybenzoic acid (5-amino-1-tosyl-pyrazol-3-yl) ester | 2,3-dimethoxybenzoic acid [5-amino-1-(4-methylphenyl)sulfonyl-3-pyrazolyl] ester | 5-amino-1-[(4-methylphenyl)sulfonyl]-1H-pyrazol-3-yl 2,3-dimethoxybenzoate | MLS000090440 | SMR000025050 | [5-amino-1-(4-methylphenyl)sulfonylpyrazol-3-yl] 2,3-dimethoxybenzoate | [5-azanyl-1-(4-methylphenyl)sulfonyl-pyrazol-3-yl] 2,3-dimethoxybenzoate | cid_3236830
Type:
Small organic molecule
Emp. Form.:
C19H19N3O6S
Mol. Mass.:
417.436
SMILES:
COc1cccc(C(=O)Oc2cc(N)n(n2)S(=O)(=O)c2ccc(C)cc2)c1OC
Structure:
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