Reaction Details Report a problem with these data
Target
Kallikrein-5
Ligand
BDBM32833
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
316.25±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM32833
Synonyms:
(4-methoxyphenyl)-(5-methylsulfanyl-3-phenyl-1,2,4-triazol-1-yl)methanone | (4-methoxyphenyl)-[5-(methylthio)-3-phenyl-1,2,4-triazol-1-yl]methanone | MLS000545911 | SMR000162943 | cid_828565 | methyl4-{[5-(methylthio)-3-phenyl-1H-1,2,4-triazol-1-yl]carbonyl}phenylether
Type:
Small organic molecule
Emp. Form.:
C17H15N3O2S
Mol. Mass.:
325.385
SMILES:
COc1ccc(cc1)C(=O)n1nc(nc1SC)-c1ccccc1
Structure:
Search PDB for entries with ligand similarity: