Reaction Details Report a problem with these data
Target
Kallikrein-5
Ligand
BDBM33906
Substrate
n/a
Meas. Tech.
Kallikrein 5 1536 HTS Dose Response Confirmation
IC50
84.44±n/a nM
Citation
 PubChem, PC Kallikrein 5 1536 HTS Dose Response Confirmation PubChem Bioassay (2008)[AID] 
Target
Name:
Kallikrein-5
Synonyms:
KLK5 | KLK5_HUMAN | Kallikrein 5 | SCTE | kallikrein-related peptidase 5 preproprotein
Type:
PROTEIN
Mol. Mass.:
32031.72
Organism:
Homo sapiens (Human)
Description:
EBI_12584
Residue:
293
Sequence:
MATARPPWMWVLCALITALLLGVTEHVLANNDVSCDHPSNTVPSGSNQDLGAGAGEDARSDDSSSRIINGSDCDMHTQPWQAALLLRPNQLYCGAVLVHPQWLLTAAHCRKKVFRVRLGHYSLSPVYESGQQMFQGVKSIPHPGYSHPGHSNDLMLIKLNRRIRPTKDVRPINVSSHCPSAGTKCLVSGWGTTKSPQVHFPKVLQCLNISVLSQKRCEDAYPRQIDDTMFCAGDKAGRDSCQGDSGGPVVCNGSLQGLVSWGDYPCARPNRPGVYTNLCKFTKWIQETIQANS
  
Inhibitor
Name:
BDBM33906
Synonyms:
5-amino-1-(4-methoxybenzoyl)pyrazole-4-carbonitrile | 5-amino-1-[(4-methoxyphenyl)-oxomethyl]-4-pyrazolecarbonitrile | 5-amino-1-p-anisoyl-pyrazole-4-carbonitrile | 5-azanyl-1-(4-methoxyphenyl)carbonyl-pyrazole-4-carbonitrile | MLS001005431 | SMR000378089 | cid_2405928
Type:
Small organic molecule
Emp. Form.:
C12H10N4O2
Mol. Mass.:
242.2334
SMILES:
COc1ccc(cc1)C(=O)n1ncc(C#N)c1N
Structure:
Search PDB for entries with ligand similarity: