Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM56842
Substrate
n/a
Meas. Tech.
Homologous Recombination - Rad 51_Dose response
IC50
85000±n/a nM
Citation
 PubChem, PC Homologous Recombination - Rad 51_Dose response PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM56842
Synonyms:
1-(2,3-dihydroindol-1-yl)-2-[[5-(phenylmethyl)-1,3,4-oxadiazol-2-yl]sulfanyl]ethanone | 1-(2,3-dihydroindol-1-yl)-2-[[5-(phenylmethyl)-1,3,4-oxadiazol-2-yl]thio]ethanone | 1-{[(5-benzyl-1,3,4-oxadiazol-2-yl)thio]acetyl}indoline | 2-[(5-benzyl-1,3,4-oxadiazol-2-yl)sulfanyl]-1-(2,3-dihydroindol-1-yl)ethanone | 2-[(5-benzyl-1,3,4-oxadiazol-2-yl)thio]-1-indolin-1-yl-ethanone | MLS000091199 | SMR000025761 | cid_2155832
Type:
Small organic molecule
Emp. Form.:
C19H17N3O2S
Mol. Mass.:
351.422
SMILES:
O=C(CSc1nnc(Cc2ccccc2)o1)N1CCc2ccccc12
Structure:
Search PDB for entries with ligand similarity: