Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM56859
Substrate
n/a
Meas. Tech.
Homologous Recombination - Rad 51_Dose response
IC50
85000±n/a nM
Citation
 PubChem, PC Homologous Recombination - Rad 51_Dose response PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM56859
Synonyms:
2-acetamido-3,3,3-trifluoro-2-[4-[(5-methyl-3-isoxazolyl)sulfamoyl]anilino]propanoic acid ethyl ester | 2-acetamido-3,3,3-trifluoro-2-[4-[(5-methylisoxazol-3-yl)sulfamoyl]anilino]propionic acid ethyl ester | MLS000547529 | SMR000113334 | cid_536731 | ethyl 2-(acetylamino)-3,3,3-trifluoro-2-(4-{[(5-methyl-3-isoxazolyl)amino]sulfonyl}anilino)propanoate | ethyl 2-acetamido-3,3,3-trifluoro-2-[4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]anilino]propanoate | ethyl 2-acetamido-3,3,3-tris(fluoranyl)-2-[[4-[(5-methyl-1,2-oxazol-3-yl)sulfamoyl]phenyl]amino]propanoate
Type:
Small organic molecule
Emp. Form.:
C17H19F3N4O6S
Mol. Mass.:
464.416
SMILES:
CCOC(=O)C(NC(C)=O)(Nc1ccc(cc1)S(=O)(=O)Nc1cc(C)on1)C(F)(F)F
Structure:
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