Reaction Details Report a problem with these data
Target
DNA repair protein RAD51 homolog 1
Ligand
BDBM43836
Substrate
n/a
Meas. Tech.
Homologous Recombination - Rad 51_Dose response
IC50
42500±n/a nM
Citation
 PubChem, PC Homologous Recombination - Rad 51_Dose response PubChem Bioassay (2008)[AID] 
Target
Name:
DNA repair protein RAD51 homolog 1
Synonyms:
RAD51 | RAD51A | RAD51_HUMAN | RECA
Type:
Enzyme Catalytic Domain
Mol. Mass.:
36960.74
Organism:
Homo sapiens (Human)
Description:
gi_49168602
Residue:
339
Sequence:
MAMQMQLEANADTSVEEESFGPQPISRLEQCGINANDVKKLEEAGFHTVEAVAYAPKKELINIKGISEAKADKILAEAAKLVPMGFTTATEFHQRRSEIIQITTGSKELDKLLQGGIETGSITEMFGEFRTGKTQICHTLAVTCQLPIDRGGGEGKAMYIDTEGTFRPERLLAVAERYGLSGSDVLDNVAYARAFNTDHQTQLLYQASAMMVESRYALLIVDSATALYRTDYSGRGELSARQMHLARFLRMLLRLADEFGVAVVITNQVVAQVDGAAMFAADPKKPIGGNIIAHASTTRLYLRKGRGETRICKIYDSPCLPEAEAMFAINADGVGDAKD
  
Inhibitor
Name:
BDBM43836
Synonyms:
Glucosamine derivative, 9 | MLS000580208 | N-(2,5-dimethoxyphenyl)-2-(8-quinolinylsulfonylamino)benzamide | N-(2,5-dimethoxyphenyl)-2-(8-quinolylsulfonylamino)benzamide | N-(2,5-dimethoxyphenyl)-2-(quinolin-8-ylsulfonylamino)benzamide | N-(2,5-dimethoxyphenyl)-2-[(8-quinolinylsulfonyl)amino]benzamide | SMR000199740 | cid_1295005
Type:
Small organic molecule
Emp. Form.:
C24H21N3O5S
Mol. Mass.:
463.506
SMILES:
COc1ccc(OC)c(NC(=O)c2ccccc2NS(=O)(=O)c2cccc3cccnc23)c1
Structure:
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