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Target
Streptokinase A
Ligand
BDBM57712
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM57712
Synonyms:
7-[3-pyridinyl-[3-(trifluoromethyl)anilino]methyl]-8-quinolinol | 7-[3-pyridyl-[3-(trifluoromethyl)anilino]methyl]quinolin-8-ol | 7-[pyridin-3-yl-[3-(trifluoromethyl)anilino]methyl]quinolin-8-ol | 7-[pyridin-3-yl-[[3-(trifluoromethyl)phenyl]amino]methyl]quinolin-8-ol | MLS000707542 | SMR000241598 | cid_4054926
Type:
Small organic molecule
Emp. Form.:
C22H16F3N3O
Mol. Mass.:
395.3771
SMILES:
Oc1c(ccc2cccnc12)C(Nc1cccc(c1)C(F)(F)F)c1cccnc1
Structure:
Search PDB for entries with ligand similarity: