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Target
Streptokinase A
Ligand
BDBM58061
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM58061
Synonyms:
(3Z)-2-(3-amylimidazol-3-ium-1-yl)-3-brosylimino-4-keto-naphthalen-1-olate | (3Z)-3-(4-bromophenyl)sulfonylimino-4-oxidanylidene-2-(3-pentylimidazol-3-ium-1-yl)naphthalen-1-olate | (3Z)-3-(4-bromophenyl)sulfonylimino-4-oxo-2-(3-pentyl-1-imidazol-3-iumyl)-1-naphthalenolate | (3Z)-3-(4-bromophenyl)sulfonylimino-4-oxo-2-(3-pentylimidazol-3-ium-1-yl)naphthalen-1-olate | MLS000768825 | SMR000432129 | cid_16411549
Type:
Small organic molecule
Emp. Form.:
C24H22BrN3O4S
Mol. Mass.:
528.418
SMILES:
CCCCC[n+]1ccn(c1)C1=C([N-]S(=O)(=O)c2ccc(Br)cc2)C(=O)c2ccccc2C1=O |c:11|
Structure:
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