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Target
Streptokinase A
Ligand
BDBM54376
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
12798±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM54376
Synonyms:
6-Hexyl-7-hydroxy-2-oxo-2H-chromene-3-carboxylic acid ethyl ester | 6-hexyl-7-hydroxy-2-keto-chromene-3-carboxylic acid ethyl ester | 6-hexyl-7-hydroxy-2-oxo-1-benzopyran-3-carboxylic acid ethyl ester | MLS000777587 | SMR000413981 | cid_5545047 | ethyl 6-hexyl-7-hydroxy-2-oxochromene-3-carboxylate | ethyl 6-hexyl-7-oxidanyl-2-oxidanylidene-chromene-3-carboxylate
Type:
Small organic molecule
Emp. Form.:
C18H22O5
Mol. Mass.:
318.3643
SMILES:
CCCCCCc1cc2cc(C(=O)OCC)c(=O)oc2cc1O
Structure:
Search PDB for entries with ligand similarity: