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Target
Streptokinase A
Ligand
BDBM58648
Substrate
n/a
Meas. Tech.
Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression
EC50
150000±n/a nM
Citation
 PubChem, PC Absorbance Microorganism-Based Dose Response HTS to Identify Inhibitors of Streptokinase Expression PubChem Bioassay (2009)[AID] 
Target
Name:
Streptokinase A
Synonyms:
STRP_STRP1 | ska | streptokinase A precursor
Type:
Enzyme Catalytic Domain
Mol. Mass.:
49924.80
Organism:
Streptococcus pyogenes M1 GAS
Description:
gi_15675770
Residue:
440
Sequence:
MKNYLSIGVIALLFALTFGTVKSVQAIAGYGWLPDRPPINNSQLVVSMAGIVEGTDKKVFINFFEIDLTSQPAHGGKTEQGLSPKSKPFATDNGAMPHKLEKADLLKAIQKQLIANVHSNDGYFEVIDFASDATITDRNGKVYFADKDGSVTLPTQPVQEFLLKGHVRVRPYKEKPVQNQAKSVDVEYTVQFTPLNPDDDFRPGLKDTKLLKTLAIGDTITSQELLAQAQSILNKTHPGYTIYERDSSIVTHDNDIFRTILPMDQEFTYHVKNREQAYEINPKTGIKEKTNNTDLVSEKYYVLKQGEKPYDPFDRSHLKLFTIKYVDVNTNELLKSEQLLTASERNLDFRDLYDPRDKAKLLYNNLDAFDIMDYTLTGKVEDNHDKNNRVVTVYMGKRPKGAKGSYHLAYDKDLYTEEERKAYSYLRDTGTPIPDNPKDK
  
Inhibitor
Name:
BDBM58648
Synonyms:
(2-benzamido-2-oxidanylidene-ethyl) 3-ethyl-5-methyl-1,2-oxazole-4-carboxylate | (2-benzamido-2-oxoethyl) 3-ethyl-5-methyl-1,2-oxazole-4-carboxylate | 3-ethyl-5-methyl-4-isoxazolecarboxylic acid (2-benzamido-2-oxoethyl) ester | 3-ethyl-5-methyl-isoxazole-4-carboxylic acid (2-benzamido-2-keto-ethyl) ester | MLS001077438 | SMR000717255 | cid_7660698
Type:
Small organic molecule
Emp. Form.:
C16H16N2O5
Mol. Mass.:
316.3086
SMILES:
CCc1noc(C)c1C(=O)OCC(=O)NC(=O)c1ccccc1
Structure:
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