Reaction Details Report a problem with these data
Target
Alkaline phosphatase, germ cell type
Ligand
BDBM39777
Substrate
n/a
Meas. Tech.
Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase
EC50
999000±n/a nM
Citation
 PubChem, PC Luminescent assay for HTS discovery of chemical activators of placental alkaline phosphatase PubChem Bioassay (2007)[AID] 
Target
Name:
Alkaline phosphatase, germ cell type
Synonyms:
ALPG | ALPPL | ALPPL2 | Alkaline phosphatase placental-like | PPBN_HUMAN | placental-like alkaline phosphatase preproprotein
Type:
PROTEIN
Mol. Mass.:
57374.31
Organism:
Homo sapiens (Human)
Description:
ChEMBL_29964
Residue:
532
Sequence:
MQGPWVLLLLGLRLQLSLGIIPVEEENPDFWNRQAAEALGAAKKLQPAQTAAKNLIIFLGDGMGVSTVTAARILKGQKKDKLGPETFLAMDRFPYVALSKTYSVDKHVPDSGATATAYLCGVKGNFQTIGLSAAARFNQCNTTRGNEVISVMNRAKKAGKSVGVVTTTRVQHASPAGAYAHTVNRNWYSDADVPASARQEGCQDIATQLISNMDIDVILGGGRKYMFPMGTPDPEYPDDYSQGGTRLDGKNLVQEWLAKHQGARYVWNRTELLQASLDPSVTHLMGLFEPGDMKYEIHRDSTLDPSLMEMTEAALLLLSRNPRGFFLFVEGGRIDHGHHESRAYRALTETIMFDDAIERAGQLTSEEDTLSLVTADHSHVFSFGGYPLRGSSIFGLAPGKARDRKAYTVLLYGNGPGYVLKDGARPDVTESESGSPEYRQQSAVPLDGETHAGEDVAVFARGPQAHLVHGVQEQTFIAHVMAFAACLEPYTACDLAPRAGTTDAAHPGPSVVPALLPLLAGTLLLLGTATAP
  
Inhibitor
Name:
BDBM39777
Synonyms:
1-(2-Ethyl-phenyl)-3-(9-thiophen-2-ylmethyl-9-aza-bicyclo[3.3.1]non-3-yl)-thiourea | 1-(2-ethylphenyl)-3-[9-(2-thenyl)-9-azabicyclo[3.3.1]nonan-3-yl]thiourea | 1-(2-ethylphenyl)-3-[9-(thiophen-2-ylmethyl)-9-azabicyclo[3.3.1]nonan-3-yl]thiourea | MLS000556774 | SMR000173331 | cid_3218177
Type:
Small organic molecule
Emp. Form.:
C22H29N3S2
Mol. Mass.:
399.616
SMILES:
[H]C12CCCC([H])(CC(C1)NC(=S)Nc1ccccc1CC)N2Cc1cccs1
Structure:
Search PDB for entries with ligand similarity: