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Target
E3 ubiquitin-protein ligase XIAP
Ligand
BDBM59494
Substrate
n/a
Meas. Tech.
Chemical Antagonists IAP-family anti-apoptotic proteins
IC50
100000±n/a nM
Citation
 PubChem, PC Chemical Antagonists IAP-family anti-apoptotic proteins PubChem Bioassay (2008)[AID] 
Target
Name:
E3 ubiquitin-protein ligase XIAP
Synonyms:
API3 | BIRC4 | E3 ubiquitin-protein ligase XIAP | IAP3 | Inhibitor of apoptosis protein 3 | Inhibitor of apoptosis protein 3 (XIAP) | X-linked inhibitor of apoptosis | X-linked inhibitor of apoptosis protein (XIAP) | XIAP | XIAP_HUMAN
Type:
Protein
Mol. Mass.:
56685.27
Organism:
Homo sapiens (Human)
Description:
P98170
Residue:
497
Sequence:
MTFNSFEGSKTCVPADINKEEEFVEEFNRLKTFANFPSGSPVSASTLARAGFLYTGEGDTVRCFSCHAAVDRWQYGDSAVGRHRKVSPNCRFINGFYLENSATQSTNSGIQNGQYKVENYLGSRDHFALDRPSETHADYLLRTGQVVDISDTIYPRNPAMYSEEARLKSFQNWPDYAHLTPRELASAGLYYTGIGDQVQCFCCGGKLKNWEPCDRAWSEHRRHFPNCFFVLGRNLNIRSESDAVSSDRNFPNSTNLPRNPSMADYEARIFTFGTWIYSVNKEQLARAGFYALGEGDKVKCFHCGGGLTDWKPSEDPWEQHAKWYPGCKYLLEQKGQEYINNIHLTHSLEECLVRTTEKTPSLTRRIDDTIFQNPMVQEAIRMGFSFKDIKKIMEEKIQISGSNYKSLEVLVADLVNAQKDSMQDESSQTSLQKEISTEEQLRRLQEEKLCKICMDRNIAIVFVPCGHLVTCKQCAEAVDKCPMCYTVITFKQKIFMS
  
Inhibitor
Name:
BDBM59494
Synonyms:
5-[2-hydroxyethyl(isopropyl)amino]-1,1-diphenyl-pent-3-yn-1-ol | 5-[2-hydroxyethyl(propan-2-yl)amino]-1,1-diphenyl-3-pentyn-1-ol | 5-[2-hydroxyethyl(propan-2-yl)amino]-1,1-diphenyl-pent-3-yn-1-ol | 5-[2-hydroxyethyl(propan-2-yl)amino]-1,1-diphenylpent-3-yn-1-ol | MLS000712067 | SMR000281834 | cid_1904109
Type:
Small organic molecule
Emp. Form.:
C22H27NO2
Mol. Mass.:
337.4553
SMILES:
CC(C)N(CCO)CC#CCC(O)(c1ccccc1)c1ccccc1
Structure:
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