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Target
Large T antigen
Ligand
BDBM40048
Substrate
n/a
Meas. Tech.
Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents
IC50
78580±n/a nM
Citation
 PubChem, PC Identification of SV40 T antigen inhibitors: A route to novel anti-viral reagents PubChem Bioassay (2010)[AID] 
Target
Name:
Large T antigen
Synonyms:
LT | LT-AG | LT_SV40
Type:
Enzyme Catalytic Domain
Mol. Mass.:
81575.54
Organism:
Simian virus 40
Description:
P03070
Residue:
708
Sequence:
MDKVLNREESLQLMDLLGLERSAWGNIPLMRKAYLKKCKEFHPDKGGDEEKMKKMNTLYKKMEDGVKYAHQPDFGGFWDATEIPTYGTDEWEQWWNAFNEENLFCSEEMPSSDDEATADSQHSTPPKKKRKVEDPKDFPSELLSFLSHAVFSNRTLACFAIYTTKEKAALLYKKIMEKYSVTFISRHNSYNHNILFFLTPHRHRVSAINNYAQKLCTFSFLICKGVNKEYLMYSALTRDPFSVIEESLPGGLKEHDFNPEEAEETKQVSWKLVTEYAMETKCDDVLLLLGMYLEFQYSFEMCLKCIKKEQPSHYKYHEKHYANAAIFADSKNQKTICQQAVDTVLAKKRVDSLQLTREQMLTNRFNDLLDRMDIMFGSTGSADIEEWMAGVAWLHCLLPKMDSVVYDFLKCMVYNIPKKRYWLFKGPIDSGKTTLAAALLELCGGKALNVNLPLDRLNFELGVAIDQFLVVFEDVKGTGGESRDLPSGQGINNLDNLRDYLDGSVKVNLEKKHLNKRTQIFPPGIVTMNEFSVPKTLQARFVKQIDFRAKDYLKHCLERSEFLLEKRIIQSGIALLLMLIWYRPVAEFAQSIQSRIVEWKERLDKEFSLSVYQKMKFNVAMGIGVLDWLRNSDDDDEDSQENADKNEDGGEKNMEDSGHETGIDSQSQGSFQAPQSSQSVHDHNQPYHICRGFTCFKKPPTPPPEPET
  
Inhibitor
Name:
BDBM40048
Synonyms:
6-bromanyl-2-(furan-2-yl)quinoline-4-carboxylic acid | 6-bromo-2-(2-furanyl)-4-quinolinecarboxylic acid | 6-bromo-2-(2-furyl)cinchoninic acid | 6-bromo-2-(2-furyl)quinoline-4-carboxylic acid | 6-bromo-2-(furan-2-yl)quinoline-4-carboxylic acid | MLS000047603 | SMR000033614 | cid_686152
Type:
Small organic molecule
Emp. Form.:
C14H8BrNO3
Mol. Mass.:
318.122
SMILES:
OC(=O)c1cc(nc2ccc(Br)cc12)-c1ccco1
Structure:
Search PDB for entries with ligand similarity: