Reaction Details Report a problem with these data
Target
G-protein coupled receptor 35
Ligand
BDBM61604
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
2411.771±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61604
Synonyms:
(Z)-2-(1H-Benzoimidazol-2-yl)-3-(5-morpholin-4-yl-furan-2-yl)-acrylonitrile | (Z)-2-(1H-benzimidazol-2-yl)-3-(5-morpholin-4-ylfuran-2-yl)prop-2-enenitrile | (Z)-2-(1H-benzimidazol-2-yl)-3-(5-morpholino-2-furyl)acrylonitrile | (Z)-2-(1H-benzimidazol-2-yl)-3-[5-(4-morpholinyl)-2-furanyl]-2-propenenitrile | MLS000528658 | SMR000121133 | cid_5768597
Type:
Small organic molecule
Emp. Form.:
C18H16N4O2
Mol. Mass.:
320.3452
SMILES:
N#C\C(=C\c1ccc(o1)N1CCOCC1)c1nc2ccccc2[nH]1
Structure:
Search PDB for entries with ligand similarity: