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Target
G-protein coupled receptor 35
Ligand
BDBM61619
Substrate
n/a
Meas. Tech.
Image-Based HTS for Selective Antagonists of GPR35
IC50
32000±n/a nM
Citation
 PubChem, PC Image-Based HTS for Selective Antagonists of GPR35 PubChem Bioassay (2010)[AID] 
Target
Name:
G-protein coupled receptor 35
Synonyms:
G protein-coupled receptor 35 | GPR35 | GPR35_HUMAN
Type:
Enzyme Catalytic Domain
Mol. Mass.:
34085.57
Organism:
Homo sapiens (Human)
Description:
gi_33695097
Residue:
309
Sequence:
MNGTYNTCGSSDLTWPPAIKLGFYAYLGVLLVLGLLLNSLALWVFCCRMQQWTETRIYMTNLAVADLCLLCTLPFVLHSLRDTSDTPLCQLSQGIYLTNRYMSISLVTAIAVDRYVAVRHPLRARGLRSPRQAAAVCAVLWVLVIGSLVARWLLGIQEGGFCFRSTRHNFNSMAFPLLGFYLPLAVVVFCSLKVVTALAQRPPTDVGQAEATRKAARMVWANLLVFVVCFLPLHVGLTVRLAVGWNACALLETIRRALYITSKLSDANCCLDAICYYYMAKEFQEASALAVAPSAKAHKSQDSLCVTLA
  
Inhibitor
Name:
BDBM61619
Synonyms:
2-[(E)-1-(benzenesulfonyl)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1H-benzimidazole | 2-[(E)-1-(phenylsulfonyl)-2-[4-(trifluoromethyl)phenyl]ethenyl]-1H-benzimidazole | 2-[(E)-1-besyl-2-[4-(trifluoromethyl)phenyl]vinyl]-1H-benzimidazole | MLS000335593 | SMR000253347 | cid_5986909
Type:
Small organic molecule
Emp. Form.:
C22H15F3N2O2S
Mol. Mass.:
428.427
SMILES:
FC(F)(F)c1ccc(\C=C(/c2nc3ccccc3[nH]2)S(=O)(=O)c2ccccc2)cc1
Structure:
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